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Please follow the instructions carefully.1- Find a peer-reviewed journal article on Nitrofurantoin
to treat urinary tract infection. 2 – Find an FDA-approved and sanctioned PDF Package Insert (PI) of Nitrofurantoin. Develop a case scenario as a Nurse Practitioner. You must address the following in your case synopsis –
what does the case tell you:
a. Is it gram negative or gram-positive organism?
b. Do you need broad coverage antibiotic, or narrow coverage – explain why?
c. Explain the MIC / MBC? .Teach the reader about the drug( Nitrofurantoin), its use, and the fundamental components of the drug (e.g., PK, PD, MOA, penetration, generation,
etcetera)
d. Explain the MOA – in detail the linkages as it relates to the organism & the diagnosis (e.g., UTI)
e. Is it chronic or acute?
f. Is it complicated with comorbidities (e.g., diabetes)?
g. Do you need surveillance labs – if so – what and when? (e.g., creatinine? Liver enzymes)
h. How will you fix your patient?
2. Take the lead in caring for the patient and provide a short case synopsis (See described later).
3. Once you detail your patient synopsis, fix your patient, and make the infection / complaint stop.
4. Recall the PPT offered in Week Number 1 – what are the components needed in a legal and safe prescription- this holds true
still.
5. You must summarize with an anticipated response to treatment – proof that you fixed your patient as promised with your
selected drug – how will you demonstrate you fixed your patient? (e.g., does your patient now have a fever? Does the
patient have a trending decrease in the WBC?)
6. Do a google search for the ICD-10 code (the billing/diagnosis code; example- J18.9- Pneumonia, unspecified; N39.0- Urinary
tract infection, site not specified; G00.9- Bacterial meningitis, unspecified).
a. Your choice – be creative – just support it with one peer-reviewed article and identify the appropriate billing code. ***Please attach a PDF copy of the article and the Package insert ***
please use the information in the article and package insert to answer the above questions.
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